Acid-Base

• Primer on clinical acid-base problem solving

Anemia in Critical Care- incl transfusions, erythropoetin (EPO)

• Anemia and Blood Transfusion in Critically Ill Patients
• Allogeneic Blood Transfusion Increases the Risk of Postoperative Bacterial Infection: A Meta-analysis
• Efficacy of recombinant human erythropoietin in the critically ill patient: A randomized,double-blind, placebo-controlled trial
• Increase Rate of Infection Associated with Transfusion of Old Blood After Severe Injury
• Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients
• The CRIT Study: Anemia and blood transfusion in the critically ill—Current clinical practice in the United States
• We also reviewed Clinical Practice Guideline: Red Blood Cell Transfusion in Trauma and Critical Care; EAST Practice Management Workgroup and the American College of Critical Care Medicine of the SCCM Taskforce but I could not find an electronic version to post here

Bowel Evacuation in Spinal Cord Injury (SCI)

• Neostigmine–Glycopyrrolate for Bowel Evacuation in SCI

Cardiology

• EKG
• MI in LBBB

C-Spine Clearance

• American College of Radiology Appropriateness Criteria, Summary of Literature Review, and Other Recommendations (e.g. NEXUS, Canadian C-Spine Rules)
• Cervical spine clearance: a review -- one of the most comprehensive reviews available
• Exclusion of Unstable Cervical Spine Injury in Obtunded Patients with Blunt Trauma: Is MR Imaging Needed when Multi–Detector Row CT Findings Are Normal?

Continuous Renal Replacement Therapy- Continuous Veno-Venous, CRRT, CVV

• A comparison of continuous renal replacement therapy to intermittent dialysis
• Cytokine removal during continuous hemofiltration in septic patients
• Early Hemodynamic Improvement is a Prognostic Marker in Patients Treated with CVVHDF for Acute Renal Failure
• Early isovolaemic haemofiltration in oliguric patients with septic shock
• Continuous renal replacement therapy improves renal recovery from acute renal failure

Daxor- Blood Volume Analysis (BVA) by Daxor Corporation - PowerPoint Presentation by Daxor to Shock Trauma Fellows January 24, 2007

Early Goal Directed Therapy (EGDT)

• UMDNJ Sepsis Flowchart-- If you have a patient who might meet criteria and you want a single-page flowchart to follow to diagnose and treat the patient, print out this file
• Manny Rivers's Paper:  Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
• The STOP Sepsis Bundle Toolkit
• Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock

Electrolytes

• Hyponatremia

Endotracheal Intubation, Prehospital

• Endotracheal Intubation in the Field Does Not Improve Outcome in Trauma Patients Who Present without an Acutely Lethal Traumatic Brain Injury
• Letter to the Editor
• The Impact of Prehospital Endotracheal Intubation on Outcome in Moderate to Severe Traumatic Brain Injury
• Immediate versus Delayed Fluid Resuscitation for Hypotensive Patients with Penetrating Torso Injuries
• Table 1
• Table 2
• Table 3
• Table 4
• Table 5
• Table 6
• Editorial published in same issue
• Correspondence (four of them) published about 4.5 months after the article

Fat Emboli Syndrome

• Therapeutic aspects of fat embolism syndrome- Habashi, Scalea
• MRI Findings in Cerebral Fat Embolism

Fenoldopam

Heart Failure

• The following are from a supplement published in the American Journal of Medicine, 2006, Vol 119 (12A)
1. Introduction
2. Congestion in Acute Heart Failure Syndromes- An Essential Target of Evaluation and Treatment.pdf
3. Pathophysiology of Volume Overload in Acute Heart
4. The Confounding Issue of Comorbid Renal Insufficiency.pdf
5. Practical Applications of Intravenous Diuretic Therapy in Decompensated Heart Failure
6. Beyond Diuretics- Management of Volume Overload in Acute Heart Failure Syndromes

Hemodynamic Concepts

• Blood Pressure Management after Acute Spinal Cord Injury
• Meta-analysis of hemodynamic optimization in high-risk patients

Hypertonic Saline

• Hypertonic Saline in TBI
• Hypertonic Saline in SAH

Necrotizing Pancreatitis

• Evidence-Based Treatment of Acute Pancreatitis: A Look at Established Paradigms

Neurotrauma

• Indicators for Tracheostomy in Patients with Traumatic Brain Injury
• Characterizing the Need for Mechanical Ventilation Following Cervical Spinal Cord Injury with Neurologic Deficit
• Tracheostomy after Anterior Cervical Spine Fixation
• Implications of Extubation Delay in Brain-Injured Patients Meeting Standard Weaning Criteria

Nutrition

• Enteral (i.e. given via the digestive tract)
• Oxepa in Acute Lung Injury
• Oxepa in ARDS

Radio-Contrast Induced Nephropathy (RCIN)

• Facts and fallacies concerning the prevention of contrast medium–induced nephropathy
• Strategies to Reduce the Risk of Contrast-Induced Nephropathy
• Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate; A Randomized Controlled Trial
• University of Maryland Guidelines
• Dispensing and Administration for CIN (Contrast Induced Nephropathy)
• Prevention of Contrast- Induced Nephropathy

Resuscitation- including fluid, endpoints, supranormal, early goal directed, and in acute lung injury

• A Comparison of Albumin and Saline for Fluid Resuscitation in the ICU
• Clinical Practice Guideline:  Endpoints of Resuscitation
• Comparison of Two Fluid-Management Strategies in Acute Lung Injury
  • Letter to the Editor- Fluid Management Strategies in Acute Lung Injury- Liberal, Conservative, or Both?
• Hemoglobin-Based Oxygen Carriers in Trauma Care:  Scientific Rationale for the US Multicenter Prehospital Trial
• Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock- Manny Rivers, NEJM 2001
• Supranormal Trauma Rescucitation Causes More Cases of Abdominal Compartment Syndrome
• Letter to the Editor- Supranormal Trauma Resucitation and Abdominal Compartment Syndrome
• Reply

Scaling system for organ specific injuries

Sepsis- Immunopathology and treatment (Surviving Sepsis Guidelines, early goal-directed therapy, norepi, steroids)

• Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock- Manny Rivers, NEJM 2001
• Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis- PROWESS Trial, Bernard, NEJM 2001
• The Immunopathogenesis of Sepsis
• Effect of Norepinephrine on the Outcome of Septic Shock
• Effect of Treatment with Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients with Septic Shock- Annane JAMA 2002
• Surviving Sepsis Guidelines for Management of Severe Sepsis and Septic Shock

Soft-tissue, Scleroderma

• Scleroderma-like Fibrosing Disorders (incl Nephrogenic Systemic Fibrosis, NSF)

Splenic Injuries, Nonoperative Management

• Nonoperative Management of Blunt Splenic Injury:  A 5-Year Experience
• Blunt Splenic Injury in Adults: Multi-institutional Study of the Eastern Association for the Surgery of Trauma
• Nonoperative Salvage of Computed Tomography--Diagnosed Splenic Injuries: Utilization of Angiography for Triage and Embolization for Hemostasis
• Changes in the Management of Injuries to the Liver and Spleen

Swan-Ganz (Pulmonary Artery or PA) Catheter

• This article (in two parts) was recommended to me as two of the better articles explaining exactly what information a Swan-Ganz catheter gives you.  Note the last author, as well as the first (Forrester was a graduate student working with Swan and Ganz during the development of their famous cathether). Both are large file sizes since the articles are too old as to be available in electronic format; these are scans of the original articles.
• Medical Therapy of Acute Myocardial Infarction by Application of Hemodynamic Subsets- First of Two Parts
• Medical Therapy of Acute Myocardial Infarction by Application of Hemodynamic Subsets- Second of Two Parts

Syncope

• San Francisco Syncope Rule
• Validation of the San Francisco Syncope Rule
• Failure to Validate the San Francisco Syncope Rule
• Death after ED Visits for Syncope

Thyrotoxic Periodic Paralysis (TPP)

• Thyrotoxic Periodic Paralysis- Clinical Review from MD Consult

Vena Cava Filters

• Clinical trial of vena caval filters in the prevention of pulmonary embolism
• Patient Patterns and Outcomes of Retrievable Vena Cava filtere
• Prevention of venous thromboembolism

Ventilator- Ventilator Weaning

• A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation
• Effect on the Duration of Mechanical Ventilation of Identifying Patients Capable of Breathing Spontaneously
• Effect of Spontaneous Breathing Trial Duration on Outcome of Attempts to Discontinue Mechanical Ventilation

Ventilator- Waveform Analysis