Meduri Steroid Protocol

Methylprednisolone (Solu-Medrol)

Methylprednisolone (Solu-Medrol)
Loading dose 2 mg/kg
Day 1 to 14 2 mg/kg/day divided q 6hrs
Day 15 to 21 1 mg/kg/day divided q 6hrs
Day 22 to 28 0.5 mg/kg/day divided q 6hrs
Days 29 and 30 0.25 mg/kg/day divided q 6hrs
Days 31 and 32 0.125 mg/kg/day divided q 6hrs

Or?

Methylprednisolone (Solu-Medrol)
Loading dose 1 mg/kg
Day 1-14 1 mg/kg/d
Day 15-21 0.5 mg/kg/d
Day 22-25 0.25 mg/kg/d
Day 26-28 0.125 mg/kg/d

If the patient extubates between days 1-14, advance to day 15 of drug therapy and tapered according to schedule.

May change to a single oral dose when oral intake is restored.